Shopping Cart
- Remove All
- Your shopping cart is currently empty
The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 μM compared to 20 μM by resveratrol.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $113 | 35 days | |
50 mg | $495 | 35 days | |
100 mg | $878 | 35 days | |
500 mg | $3,820 | 35 days |
Description | The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 μM compared to 20 μM by resveratrol. |
Molecular Weight | 228.266 |
Formula | C15H13FO |
Cas No. | 139141-12-1 |
Relative Density. | 1.136 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMF:PBS (pH 7.2) (1:2): 0.3 mg/mL (1.31 mM), Sonication is recommended. DMSO: 2 mg/mL (8.76 mM), Sonication is recommended. Ethanol: 0.5 mg/mL (2.19 mM), Sonication is recommended. DMF: 3 mg/mL (13.14 mM), Sonication is recommended. |
Solution Preparation Table | |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.