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CBHA
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Catalog No. T21719Cas No. 174664-65-4
m-Carboxycinnamic acid bishydroxamide, an effective HDAC inhibitor, shows ID50 values of 10 nM for HDAC1 and 70 nM for HDAC3 in vitro, demonstrating its potent activity. Additionally, it promotes apoptosis and inhibits tumor growth, highlighting its therapeutic potential [1][2].
CBHA
😃Good
Catalog No. T21719Cas No. 174664-65-4
m-Carboxycinnamic acid bishydroxamide, an effective HDAC inhibitor, shows ID50 values of 10 nM for HDAC1 and 70 nM for HDAC3 in vitro, demonstrating its potent activity. Additionally, it promotes apoptosis and inhibits tumor growth, highlighting its therapeutic potential [1][2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $198 | 35 days | |
| 10 mg | $383 | 35 days | |
| 25 mg | $588 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | m-Carboxycinnamic acid bishydroxamide, an effective HDAC inhibitor, shows ID50 values of 10 nM for HDAC1 and 70 nM for HDAC3 in vitro, demonstrating its potent activity. Additionally, it promotes apoptosis and inhibits tumor growth, highlighting its therapeutic potential [1][2]. |
| Molecular Weight | 222.2 |
| Formula | C10H10N2O4 |
| Cas No. | 174664-65-4 |
| Relative Density. | 1.431g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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