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CDK7-IN-6

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Catalog No. T39943Cas No. 2378710-04-2
Alias CDK7-IN-6

CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. This compound holds significant potential for cancer research purposes.

CDK7-IN-6

CDK7-IN-6

😃Good
Catalog No. T39943Alias CDK7-IN-6Cas No. 2378710-04-2
CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. This compound holds significant potential for cancer research purposes.
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Product Introduction

Bioactivity
Description
CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. This compound holds significant potential for cancer research purposes.
Targets&IC50
CDK7:≤100 nM (IC50)
In vitro
CDK7-IN-6 effectively suppresses cell viability in various cancer cell lines, including HCT116, H460, MV4-11, A2780, and OVCAR cells, demonstrating potent inhibition (IC50 ≤1 μM)[1].
AliasCDK7-IN-6
Chemical Properties
Molecular Weight524.07
FormulaC26H34ClN9O
Cas No.2378710-04-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

CDK7IN6CDK-7-IN-6CDK7 IN 6
Related Tags: buy CDK7-IN-6 | purchase CDK7-IN-6 | CDK7-IN-6 cost | order CDK7-IN-6 | CDK7-IN-6 chemical structure | CDK7-IN-6 in vitro | CDK7-IN-6 formula | CDK7-IN-6 molecular weight
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