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CDK7-IN-7

Catalog No. T40264Cas No. 2640208-01-9
Alias CDK7-IN-7

CDK7-IN-7, a highly potent and selective inhibitor of CDK7 kinase, exhibits remarkable activity with an IC50 of less than 50 nM.

CDK7-IN-7

CDK7-IN-7

Catalog No. T40264Alias CDK7-IN-7Cas No. 2640208-01-9
CDK7-IN-7, a highly potent and selective inhibitor of CDK7 kinase, exhibits remarkable activity with an IC50 of less than 50 nM.
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5 mg$970Backorder
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Product Introduction

Bioactivity
Description
CDK7-IN-7, a highly potent and selective inhibitor of CDK7 kinase, exhibits remarkable activity with an IC50 of less than 50 nM.
Targets&IC50
CDK7:<50 nM (IC50)
In vitro
CDK7-IN-7 exhibits inhibitory activity against MDA-MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr, and Calu-6 cells (IC 50 ranging from 12.21 to 144.9 nM) [1].
AliasCDK7-IN-7
Chemical Properties
Molecular Weight513.319
FormulaC20H20BrF3N6O2
Cas No.2640208-01-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CDK7 IN 7CDK-7-IN-7CDK7IN7
Related Tags: buy CDK7-IN-7 | purchase CDK7-IN-7 | CDK7-IN-7 cost | order CDK7-IN-7 | CDK7-IN-7 chemical structure | CDK7-IN-7 in vitro | CDK7-IN-7 formula | CDK7-IN-7 molecular weight
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