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Ceanothic acid

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Catalog No. TN1477Cas No. 21302-79-4

Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines.

Ceanothic acid

Ceanothic acid

😃Good
Catalog No. TN1477Cas No. 21302-79-4
Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines.
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5 mg$2,450Backorder
1 mL x 10 mM (in DMSO)$2,998Backorder
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Product Introduction

Bioactivity
Description
Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines.
In vitro
Six ceanothane and 1-norceanothane derivatives (1, 2, 8-11) were prepared from Ceanothic acid dibenzyl ester. These ring-A homologues of betulinic acid exhibited cytotoxic effects. Among these, 1-decarboxy-3-oxo-Ceanothic acid (2) was found to be the most cytotoxic against OVCAR-3 and HeLa cancer cell lines, with an IC50 of 2.8 and 6.6 microg/mL, respectively, and an IC50 of 11.3 microg/mL against normal cell line FS-5.
Chemical Properties
Molecular Weight486.693
FormulaC30H46O5
Cas No.21302-79-4
Relative Density.1.149 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

Ceanothic acid
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