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CENTA

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Catalog No. T30792Cas No. 80072-86-2

CENTA is a newly synthesized β-lactamase-unstable colorimetric cephalosporin reagent that is readily hydrolyzed by all classes of β-lactamases except Aeromonas hydrophila metalloenzymes.

CENTA

CENTA

😃Good
Catalog No. T30792Cas No. 80072-86-2
CENTA is a newly synthesized β-lactamase-unstable colorimetric cephalosporin reagent that is readily hydrolyzed by all classes of β-lactamases except Aeromonas hydrophila metalloenzymes.
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1 mg$7835 days
5 mg$27335 days
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Product Introduction

Bioactivity
Description
CENTA is a newly synthesized β-lactamase-unstable colorimetric cephalosporin reagent that is readily hydrolyzed by all classes of β-lactamases except Aeromonas hydrophila metalloenzymes.
In vitro
Proteus mirabilis, Klebsiella spp., Escherichia coli, and Citrobacter diversus strains were significantly inhibited by CENTA (MIC for 50% of isolates [MIC50] = 32 μg/ml). CENTA showed the best anti-Haemophilus activity, generally 16- to 128-fold more potent than either PADAC or nitrocefin. [1]
Chemical Properties
Molecular Weight535.57
FormulaC21H17N3O8S3
Cas No.80072-86-2
SmilesOC(C1=C(CSC2=CC(C(O)=O)=C(C=C2)[N+]([O-])=O)CS[C@@]([C@@H]3NC(CC4=CC=CS4)=O)([H])N1C3=O)=O
Relative Density.1.72 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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