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CEP-5214 is a potent, low-nanomolar pan inhibitor of human VEGF-R tyrosine kinases, displaying IC50 values of 16,8, and 4 nM for VEGF-R1/FLT-1, VEGF-R2/KDR, and VEGF-R3/FLT-4, respectively, with cellular activity equivalent to the isolated enzyme activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $1,980 | 3-6 months | |
50 mg | $3,780 | 3-6 months | |
100 mg | $5,200 | 3-6 months |
Description | CEP-5214 is a potent, low-nanomolar pan inhibitor of human VEGF-R tyrosine kinases, displaying IC50 values of 16,8, and 4 nM for VEGF-R1/FLT-1, VEGF-R2/KDR, and VEGF-R3/FLT-4, respectively, with cellular activity equivalent to the isolated enzyme activity. |
Molecular Weight | 440.53 |
Formula | C28H28N2O3 |
Cas No. | 402857-39-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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