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Cevostamab

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Catalog No. T76998Cas No. 2249888-53-5

Cevostamab (BFCR4350A; RG6160; RO7187797), a humanized IgG1-based bi-specific antibody (BsAb), specifically targets the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells and CD3 on T cells. It enhances synapse formation and augments T cell-mediated killing of MM tumor cells [1] [2].

Cevostamab

Cevostamab

😃Good
Catalog No. T76998Cas No. 2249888-53-5
Cevostamab (BFCR4350A; RG6160; RO7187797), a humanized IgG1-based bi-specific antibody (BsAb), specifically targets the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells and CD3 on T cells. It enhances synapse formation and augments T cell-mediated killing of MM tumor cells [1] [2].
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Description
Cevostamab (BFCR4350A; RG6160; RO7187797), a humanized IgG1-based bi-specific antibody (BsAb), specifically targets the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells and CD3 on T cells. It enhances synapse formation and augments T cell-mediated killing of MM tumor cells [1] [2].
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Cas No.2249888-53-5
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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