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CH2COOH-PEG3-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | CH2COOH-PEG3-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, consisting of two distinct ligands linked together—one for an E3 ubiquitin ligase and the other for a target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | CH2COOH-PEG3-CH2COOH |
Molecular Weight | 266.25 |
Formula | C10H18O8 |
Cas No. | 32775-08-9 |
Relative Density. | 1.278 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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