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Chlorpheniramine
Catalog No. T60498Cas No. 132-22-9
Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases.
Chlorpheniramine
Catalog No. T60498Cas No. 132-22-9
Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 1-2 weeks | |
| 50 mg | $1,980 | 1-2 weeks | |
| 100 mg | $2,500 | 1-2 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases. |
| In vitro | Chlorpheniramine inhibits proton currents in murine microglial BV2 cells with an IC50 of 43 μM. A concentration of 100 μM for 5 minutes resulted in moderate potency inhibition of proton currents [1]. |
| In vivo | Chlorpheniramine administered intramuscularly (IM) at dosages of 50, 100, and 200 μg/kg, three times at weekly intervals, was observed to increase the count of white blood cells in the peripheral blood of Sprague-Dawley (SD) rats [2]. This elevation in white blood cells was primarily attributed to an increase in B cells and monocytes, with no significant impact on T cells and NK cells. |
| Molecular Weight | 274.79 |
| Formula | C16H19ClN2 |
| Cas No. | 132-22-9 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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