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Cholesterol glucuronide

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Catalog No. T10805Cas No. 17435-78-8

Cholesterol glucuronide is an endogenous lipid metabolite generated by UDP-gluconyltransferase in the liver.

Cholesterol glucuronide

Cholesterol glucuronide

😃Good
Catalog No. T10805Cas No. 17435-78-8
Cholesterol glucuronide is an endogenous lipid metabolite generated by UDP-gluconyltransferase in the liver.
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Product Introduction

Bioactivity
Description
Cholesterol glucuronide is an endogenous lipid metabolite generated by UDP-gluconyltransferase in the liver.
In vivo
Cholesterol glucuronide is produced in the liver, with a portion entering the bloodstream and the remainder likely being secreted into the bile, similar to other glucuronides. It is found in greater concentrations in the normal liver compared to plasma, with reported values of 18 μg/g and 6 μg/mL, respectively [1].
Chemical Properties
Molecular Weight562.78
FormulaC33H54O7
Cas No.17435-78-8
Relative Density.1.19 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Cholesterol glucuronide
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