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Cinpanemab

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Catalog No. T76861Cas No. 2094516-02-4
Alias BIIB054

Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.

Cinpanemab

Cinpanemab

🥰Excellent
Catalog No. T76861Alias BIIB054Cas No. 2094516-02-4
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.
Pack SizePriceAvailabilityQuantity
1 mg$197In Stock
5 mg$516In Stock
10 mg$828In Stock
25 mg$1,230In Stock
50 mg$1,650In Stock
100 mg$2,230In Stock
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Concentration:11.4 mg/mL
Purity:> 95%
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Product Introduction

Bioactivity
Description
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.
In vitro
Cinpanemab exhibits high selectivity for aggregated forms of α-syn, with at least an 800-fold higher apparent affinity for fibrillar recombinant α-syn compared to monomeric recombinant α-syn, and it shows a strong preference for human Parkinson's disease (PD) brain tissue[2].
In vivo
Cinpanemab (30 mg/kg; intraperitoneal injection) ameliorates Parkinson's disease (PD)-like phenotypes in a mouse model inoculated with α-syn PFFs[2].
AliasBIIB054
Chemical Properties
Molecular Weight150 kDa
Cas No.2094516-02-4
Storage & Solubility Information
Storagestore at low temperature | store at -80°C | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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