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Cirazoline hydrochloride

Name: Cirazoline hydrochloride
Brand: TargetMol
SKU: T14972
Rating: 4.5 (1 reviews)

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Catalog No. T14972Cas No. 40600-13-3

Alias LD 3098 hydrochloride

Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).

Cirazoline hydrochloride

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Catalog No. T14972Alias LD 3098 hydrochlorideCas No. 40600-13-3

Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).

Pack Size	Price	Availability
25 mg	$987	6-8 weeks
50 mg	$1,320	6-8 weeks
100 mg	$1,990	6-8 weeks

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Product Introduction

Bioactivity

Description	Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).
In vitro	Cirazoline hydrochloride (5-10 μM; 24 hours) neither affects GIC survival nor effectively counteracts prazosin‐induced GIC death[1].
In vivo	Cirazoline hydrochloride (drinking water; 40 μM; 9 months) significantly reduces immobility in the TST and enhances neurogenesis in mice [1].
Alias	LD 3098 hydrochloride

Chemical Properties

Molecular Weight	252.74
Formula	C₁₃H₁₇ClN₂O
Cas No.	40600-13-3
Relative Density.	1.25g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Cirazoline HydrochlorideCirazoline hydrochlorideLD 3098 HydrochlorideLD3098 HydrochlorideLD-3098 Hydrochloride