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Cl-PEG4-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | 5 days |
Description | Cl-PEG4-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are compounds that consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Cl-PEG4-acid |
Molecular Weight | 270.71 |
Formula | C10H19ClO6 |
Cas No. | 158553-98-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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