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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,120 | 8-10 weeks | |
50 mg | $2,780 | 8-10 weeks | |
100 mg | $3,700 | 8-10 weeks |
Description | CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM). |
In vivo | In the acute and chronic TPA models, topical treatment with CMI-392 results in a significant decrease of ear weight, inflammatory cell infiltration, and histological examination. The ED50 for PAF-induced mouse hemoconcentration and arachidonic acid-induced mouse ear edema are 2.2 and 1.8 mg/kg, respectively. |
Molecular Weight | 633.15 |
Formula | C31H37ClN2O8S |
Cas No. | 205654-37-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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