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MHI-148

Name: MHI-148
Brand: TargetMol
SKU: T77553
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T77553Cas No. 172971-76-5

Alias IR-808

MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.MHI-148 is taken up and accumulates in the lysosomes and mitochondria of tumor cells but is not taken up in the lysosomes and mitochondria of normal cells.MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection and diagnosis of cancer.

MHI-148

Purity: 95.75%

Catalog No. T77553Alias IR-808Cas No. 172971-76-5

Pack Size	Price	Availability	Quantity
25 mg	$35	In Stock
50 mg	$60	In Stock

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Purity:95.75%

Resource Download

COA HPLC HNMR

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.MHI-148 is taken up and accumulates in the lysosomes and mitochondria of tumor cells but is not taken up in the lysosomes and mitochondria of normal cells.MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection and diagnosis of cancer.
In vitro	Compound MHI-148 (10 µM; 1 h) demonstrates notably higher absorption in HT-29 colon carcinoma cells compared to normal NIH3T3 fibroblasts.[1] alongside its capacity for tumor imaging and targeted properties.[1] Compound MHI-148 (0-1.5 µM; 3 days) exhibits only negligible toxicity in both HT-29 and NIH3T3 cells.[1]
Alias	IR-808

Chemical Properties

Molecular Weight	764.23
Formula	C₄₂H₅₂BrClN₂O₄
Cas No.	172971-76-5

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 18.7 mg/mL (24.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3085 mL	6.5425 mL	13.0851 mL	65.4253 mL
5 mM	0.2617 mL	1.3085 mL	2.6170 mL	13.0851 mL
10 mM	0.1309 mL	0.6543 mL	1.3085 mL	6.5425 mL
20 mM	0.0654 mL	0.3271 mL	0.6543 mL	3.2713 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MHI148CompoundMHI148MHI-148MHI 148