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Corynecin I

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Catalog No. T38333Cas No. 4423-58-9

Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.

Corynecin I

Corynecin I

😃Good
Catalog No. T38333Cas No. 4423-58-9
Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.
Pack SizePriceAvailabilityQuantity
1 mg$253 35 days
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Questions
QWhat should I do if the product colors are different after multiple purchases?
AFirst, please confirm the batch number. If it's the same batch, please verify the product's color with our technical specialist. If they are from different batches, the color difference may result from variations in the manufacturing process. Factors such as operations, temperature, and duration during production could influence the color. If you have concerns about a specific batch, please download the corresponding quality inspection report from our official website. We take full responsibility for the quality.
QWhat equipment should be used for ultrasound?
AUltrasonic cleaners" are recommended instead of "ultrasonic disruptors".
QWhat do "mg/mL" and "mM" mean?
Amg/mL" and "mM" are two different units of measurement, but represent the same maximum solubility. You can convert between them using the molar concentration calculator on our website.
QCan high-temperature sterilization be used for inhibitors?
AMost products are synthesized by chemical methods
QIf the product does not dissolve even when it is below the maximum solubility stated in the instructions, what should I do?
AIt is recommended to utilize some auxiliary dissolution methods, such as heating to 45°C or using sonication to accelerate dissolution.
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Product Introduction

Bioactivity
Description
Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.
Chemical Properties
Molecular Weight254.24
FormulaC11H14N2O5
Cas No.4423-58-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

References

1.Yap TA, et al. Curr Opin Pharmacol. 2015 Aug;23:98-107.2.Yea SS, et al. PLoS One. 2014 Jun 10;9(6):e199486.3.So L, et al. J Biol Chem. 2013 Feb 22;288(8):5718-31.

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Corynecin I
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