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CP-319340(free base)

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Catalog No. T13418Cas No. 186390-35-2

CP-319340 free base is an inhibitor of microsomal triglyceride transfer protein (MTP).

CP-319340(free base)

CP-319340(free base)

😃Good
Catalog No. T13418Cas No. 186390-35-2
CP-319340 free base is an inhibitor of microsomal triglyceride transfer protein (MTP).
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
CP-319340 free base is an inhibitor of microsomal triglyceride transfer protein (MTP).
In vitro
Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are essential for lipoprotein assembly. MTP binds ApoB with high affinity through ionic interactions and engages at multiple sites in the N-terminal beta alpha domain of ApoB[3].
Chemical Properties
Molecular Weight476.49
FormulaC27H23F3N4O
Cas No.186390-35-2
Relative Density.1.342 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

MTPCP-319340(free base)CP319340(free base)CP 319340(free base)
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