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Cryogenine is an alkaloid originally isolated from H. salicifolia that exhibits anti-inflammatory activity. It inhibits prostaglandin synthetase (IC50 = 424 μM) and, at a dosage of 100 mg/kg per day (p.o.), reduces paw edema and the mean arthritic index in a rat model of adjuvant-induced polyarthritis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $383 | 35 days | |
5 mg | $1,710 | 35 days | |
10 mg | $2,840 | 35 days |
Description | Cryogenine is an alkaloid originally isolated from H. salicifolia that exhibits anti-inflammatory activity. It inhibits prostaglandin synthetase (IC50 = 424 μM) and, at a dosage of 100 mg/kg per day (p.o.), reduces paw edema and the mean arthritic index in a rat model of adjuvant-induced polyarthritis. |
Molecular Weight | 435.52 |
Formula | C26H29NO5 |
Cas No. | 10308-13-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMF: 30 mg/mL (68.88 mM), Sonication is recommended. DMSO: 30 mg/mL (68.88 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL (0.57 mM), Sonication is recommended. |
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