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CSV0C018875
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CSV0C018875
Catalog No. T60786Cas No. 442150-41-6
CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor with lower cytotoxicity than BIX-01294 [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks |
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor with lower cytotoxicity than BIX-01294 [1]. |
| In vitro | CSV0C018875, at concentrations ranging from 2.5 to 20 μM over a 48-hour period, reduces H3K9me2 modification levels in histones [1]. Through Western Blot Analysis [1] conducted on HEK293 cells, with doses of 2.5 μM, 10 μM, and 20 μM, it was observed that CSV0C018875 progressively inhibits G9a enzymatic activity in a dose-dependent manner. |
| Molecular Weight | 312.79 |
| Formula | C18H17ClN2O |
| Cas No. | 442150-41-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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