Name: Cyclo(Ala-Tyr)
Brand: TargetMol
SKU: TN6688
Rating: 4.5 (1 reviews)

Pack Size

Price

Availability

Quantity

10 mg

$730

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1 mL x 10 mM (in DMSO)

$500

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QIf the product does not dissolve even when it is below the maximum solubility stated in the instructions, what should I do?

AIt is recommended to utilize some auxiliary dissolution methods, such as heating to 45°C or using sonication to accelerate dissolution.

QHow should inhibitors be dissolved for cell experiments?

AInhibitors are typically dissolved in DMSO to prepare a concentrated stock solution. Please store at -80°C and aliquot the product to avoid repeated freeze-thaw cycles. For short-term use within one week, aliquots can be stored at 4°C. When diluting in experiments, PBS, physiological saline, culture medium, and water are commonly used. (Note: In cell experiments, the final concentration of DMSO should not exceed 0.1%. If it exceeds 0.1%, it's necessary to conduct a negative control experiment during preliminary test to assess any potential effects of the solvent on cells.)

QCan PEG400 be used instead of PEG300?

APEG300 has moderate viscosity, which facilitates the dissolution and administration of drugs, while also providing good tolerability without adverse effects on animals. PEG400 can replace PEG300. PEG600 is not very recommended because its melting point is close to room temperature.

QWhat's the meaning of "< 1 mg/mL refers to the slightly soluble or insoluble"?

AIt means that if the solubility is less than 1 mg/mL

QIs there a need to weigh and prepare stock solutions upon receiving the product?

AFor small packages(1 mg, 5 mg, 10 mg, etc.）, it is not recommended to weigh them again which may lead to compound loss and inaccurate measurement. Our products are imported in their original packaging and accurately weighed, so you can directly dissolve the compound in the appropriate solvent upon receipt. For large packages, you can weigh and prepare stock solutions. It is recommended to start with at least 10 mg to reduce error. If conditions permit, you can first prepare a high-concentration stock solution and then aliquot it for use

Product Introduction

Bioactivity

Description

Cyclo(Val-Tyr) is a product from the culture of Pseudomonas putida.

Chemical Properties

Molecular Weight	234.255
Formula	C₁₂H₁₄N₂O₃
Cas No.	21754-26-7
Relative Density.	1.244 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.