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CycLuc1

Name: CycLuc1
Brand: TargetMol
SKU: T15030
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15030Cas No. 1247879-16-8

CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.

CycLuc1

🥰Excellent

Purity: 95.51%

Catalog No. T15030Cas No. 1247879-16-8

CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.

Pack Size	Price	Availability
5 mg	$40	In Stock
10 mg	$64	In Stock
1 mL x 10 mM (in DMSO)	$44	In Stock

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Purity:95.51%

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COA HNMR HPLC

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Product Introduction

Bioactivity

Description

CycLuc1, a brain-penetrant luciferase substrate, may be a superior BLI substrate compared to D-luciferin for monitoring tumor growth in intracranial GBM (glioblastoma) xenografts.

Chemical Properties

Molecular Weight	305.38
Formula	C₁₃H₁₁N₃O₂S₂
Cas No.	1247879-16-8
Smiles	OC(=O)[C@H]1CSC(=N1)c1nc2cc3CCNc3cc2s1
Relative Density.	1.84 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 83.33 mg/mL (272.87 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2746 mL	16.3730 mL	32.7461 mL	163.7304 mL
5 mM	0.6549 mL	3.2746 mL	6.5492 mL	32.7461 mL
10 mM	0.3275 mL	1.6373 mL	3.2746 mL	16.3730 mL
20 mM	0.1637 mL	0.8187 mL	1.6373 mL	8.1865 mL
50 mM	0.0655 mL	0.3275 mL	0.6549 mL	3.2746 mL
100 mM	0.0327 mL	0.1637 mL	0.3275 mL	1.6373 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Reactive Oxygen SpeciesLuciferaseInhibitorinhibitCycLuc-1CycLuc1CycLuc 1