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Cytochalasin E
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Catalog No. T15039Cas No. 36011-19-5
Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of actin filaments to prevent actin elongation.
Cytochalasin E
😃Good
Catalog No. T15039Cas No. 36011-19-5
Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of actin filaments to prevent actin elongation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $168 | 35 days | |
| 5 mg | $665 | 35 days | |
| 10 mg | $1,240 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of actin filaments to prevent actin elong |
| In vitro | Cytochalasin E significantly inhibits A549 cell growth in a dose-dependent manner and induces upregulation of autophagy-related protein (LC3-II) and SQSTM1/p62 [3]. |
| Molecular Weight | 495.56 |
| Formula | C28H33NO7 |
| Cas No. | 36011-19-5 |
| Relative Density. | 1.3g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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