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D228 is an orally-administered anti-inflammatory compound effective against inflammatory bowel disease (IBD). It reduces ConA-induced T lymphocyte proliferation (IC50: 42.85 μM) and LPS-induced B lymphocyte proliferation (IC50: 3.15 μM). D228 alleviates inflammation in IBD models induced by DSS by downregulating the MyD88/TRAF6/p38 signaling pathway.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | D228 is an orally-administered anti-inflammatory compound effective against inflammatory bowel disease (IBD). It reduces ConA-induced T lymphocyte proliferation (IC50: 42.85 μM) and LPS-induced B lymphocyte proliferation (IC50: 3.15 μM). D228 alleviates inflammation in IBD models induced by DSS by downregulating the MyD88/TRAF6/p38 signaling pathway. |
Molecular Weight | 484.45 |
Formula | C22H28O12 |
Cas No. | 2676188-98-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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