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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Dazopride [LY-237733, AHR-5531] is an antiemetic agent with the chemical composition C15H15N5O2S and a molecular weight of 329.38 g/mol. It appears as white to off-white crystalline powder, melting at 159–162°C, and is soluble in water (forceps method) and organic solvents (chlorinated solvents). |
In vivo | Dasopride (0.3 mg / kg) can significantly enhance gastric emptying. In the gastric emptying test, its efficacy is about six times higher than that of metoclopramide. Dazopril (0.3-10.0 mg / kg, intravenous) produced dose-related increases in anal motility mainly by increasing the anal contraction amplitude in three sober dogs. Dazopril significantly reduced the frequency of vomiting in the control group. Doxolipril (5 mg / kg, intraperitoneal injection) antagonizes tetralin induced vomiting, but not 0.25-2.5 mg / kg. Although larger doses of 1.0 mg / kg eliminated or weakened its response, dazopril could not change cisplatin-induced vomiting at 0.1 mg / kg (iv), while dazopride at 5.0 mg / kg antagonized vomiting in all animals development of. |
Alias | AHR-5531 |
Molecular Weight | 326.82 |
Formula | C15H23ClN4O2 |
Cas No. | 70181-03-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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