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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | DBCO-PEG1, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands joined by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 348.4 |
Formula | C21H20N2O3 |
Cas No. | 1839049-33-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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