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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DBCO-PEG2-amine is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two distinct ligands linked together: one binding to an E3 ubiquitin ligase and the other to a target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 435.52 |
Formula | C25H29N3O4 |
Cas No. | 2250216-96-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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