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Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DBCO-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | DBCO-PEG4-acid |
Molecular Weight | 552.624 |
Formula | C30H36N2O8 |
Cas No. | 2110448-99-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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