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DBCO-PEG4-Biotin

DBCO-PEG4-Biotin
DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).
Catalog No. T15069Cas No. 1255942-07-4
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Purity:96.19%
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DBCO-PEG4-Biotin

Catalog No. T15069Alias ADIBO-NH-PEG2-BiotinCas No. 1255942-07-4

DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).
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Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$89In Stock
10 mg$138In Stock
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Product Introduction

Bioactivity
Description
DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).
In vitro
The alkyne group reacts with the azide moiety in a copper-free Click Chemistry reaction to form a stable triazole linkage.[1]
AliasADIBO-NH-PEG2-Biotin
Chemical Properties
Molecular Weight749.92
FormulaC39H51N5O8S
Cas No.1255942-07-4
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 74.99 mg/mL (100 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3335 mL6.6674 mL13.3348 mL66.6738 mL
5 mM0.2667 mL1.3335 mL2.6670 mL13.3348 mL
10 mM0.1333 mL0.6667 mL1.3335 mL6.6674 mL
20 mM0.0667 mL0.3334 mL0.6667 mL3.3337 mL
50 mM0.0267 mL0.1333 mL0.2667 mL1.3335 mL
100 mM0.0133 mL0.0667 mL0.1333 mL0.6667 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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