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Deac-SS-Biotin

Catalog No. T82596

Deac-SS-Biotin, a potent antitumor compound, enters cells via biotin-mediated internalization and, when combined with DTT (Glutathione mimetic), effectively inhibits microtubule assembly, exhibiting enhanced antitumor activity [1].

Deac-SS-Biotin

Deac-SS-Biotin

Catalog No. T82596
Deac-SS-Biotin, a potent antitumor compound, enters cells via biotin-mediated internalization and, when combined with DTT (Glutathione mimetic), effectively inhibits microtubule assembly, exhibiting enhanced antitumor activity [1].
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Product Introduction

Bioactivity
Description
Deac-SS-Biotin, a potent antitumor compound, enters cells via biotin-mediated internalization and, when combined with DTT (Glutathione mimetic), effectively inhibits microtubule assembly, exhibiting enhanced antitumor activity [1].
In vitro
Deac-SS-Biotin (compound 9) exhibited notable reduction-responsive drug release at a concentration of 5 µM after 24 hours of exposure [1].
Chemical Properties
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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