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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Diketone-PEG12-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs feature two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets a specific protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade these target proteins[1]. |
Molecular Weight | 1092.27 |
Formula | C58H81N3O17 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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