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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Diketone-PEG4-Biotin is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two ligands linked by a connector: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 678.84 |
Formula | C33H50N4O9S |
Cas No. | 2353409-85-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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