Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Dimethyldioctadecylammonium (bromide)

😃Good
Catalog No. T36357Cas No. 3700-67-2

Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB). DDA has also been used in the study of lipid bilayer dynamics.

Dimethyldioctadecylammonium (bromide)

Dimethyldioctadecylammonium (bromide)

😃Good
Catalog No. T36357Cas No. 3700-67-2
Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB). DDA has also been used in the study of lipid bilayer dynamics.
Pack SizePriceAvailabilityQuantity
10 g$294 35 days
50 g$1,180 35 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB). DDA has also been used in the study of lipid bilayer dynamics.
Chemical Properties
Molecular Weight630.95
FormulaC38H80BrN
Cas No.3700-67-2
Relative Density.1.047 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 33 mg/mL (52.3 mM), Sonication is recommended.
DMSO: 16 mg/mL (25.36 mM), Sonication is recommended.
DMF: 2 mg/mL (3.17 mM), Sonication is recommended.
PBS (pH 7.2): 5 mg/mL (7.92 mM), Sonication is recommended.
Solution Preparation Table
DMF/PBS (pH 7.2)/DMSO/Ethanol
1mg5mg10mg50mg
1 mM1.5849 mL7.9246 mL15.8491 mL79.2456 mL
PBS (pH 7.2)/DMSO/Ethanol
1mg5mg10mg50mg
5 mM0.3170 mL1.5849 mL3.1698 mL15.8491 mL
DMSO/Ethanol
1mg5mg10mg50mg
10 mM0.1585 mL0.7925 mL1.5849 mL7.9246 mL
20 mM0.0792 mL0.3962 mL0.7925 mL3.9623 mL
Ethanol
1mg5mg10mg50mg
50 mM0.0317 mL0.1585 mL0.3170 mL1.5849 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Dimethyldioctadecylammonium (bromide) | purchase Dimethyldioctadecylammonium (bromide) | Dimethyldioctadecylammonium (bromide) cost | order Dimethyldioctadecylammonium (bromide) | Dimethyldioctadecylammonium (bromide) chemical structure | Dimethyldioctadecylammonium (bromide) formula | Dimethyldioctadecylammonium (bromide) molecular weight