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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $123 | 35 days | |
5 mg | $950 | 35 days |
Description | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization. |
Molecular Weight | 386.51 |
Formula | C19H26N6OS |
Cas No. | 361431-33-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL Ethanol: 20 mg/mL DMSO: 30 mg/mL DMF: 30 mg/mL |
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