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DL-AP7, a competitive NMDA antagonist and anticonvulsant, blocks NMDA-induced convulsions and impairs learning performance in mice during a passive avoidance task [1].
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Description | DL-AP7, a competitive NMDA antagonist and anticonvulsant, blocks NMDA-induced convulsions and impairs learning performance in mice during a passive avoidance task [1]. |
In vivo | DL-AP7, when administered intracerebroventricularly (ICV), inhibits convulsions triggered by NMDA with an effective dose (ED 50) of 0.22 nmol/mouse. Additionally, it detrimentally affects the ability of mice to learn in a passive avoidance task [1]. |
Molecular Weight | 225.181 |
Formula | C7H16NO5P |
Cas No. | 85797-13-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | 1eq. NaOH: 100 mM | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
1eq. NaOH
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