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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DSPE-PEG4-acid is a PEG-based linker (for PROTACs) that connects two essential ligands, playing a crucial role in the formation of PROTAC molecules, and facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins [1]. |
Molecular Weight | 1010.32 |
Formula | C52H100NO15P |
Cas No. | 2112738-58-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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