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DSPE-PEG46-N3, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DSPE-PEG46-N3, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two ligands linked by a connector: one targeting an E3 ubiquitin ligase and the other the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 2843.51 |
Formula | C134H265N4O55P |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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