Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Dutogliptin

😃Good
Catalog No. T11128Cas No. 852329-66-9
Alias PHX-1149 free base

Dutogliptin (PHX-1149 free base) is an effective, selective oral dipeptidyl peptidase-4 (DPP4) inhibitor used for treating type 2 diabetes mellitus.

Dutogliptin

Dutogliptin

😃Good
Catalog No. T11128Alias PHX-1149 free baseCas No. 852329-66-9
Dutogliptin (PHX-1149 free base) is an effective, selective oral dipeptidyl peptidase-4 (DPP4) inhibitor used for treating type 2 diabetes mellitus.
Pack SizePriceAvailabilityQuantity
5 mg$813Backorder
10 mg$1,240Backorder
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Dutogliptin (PHX-1149 free base) is an effective, selective oral dipeptidyl peptidase-4 (DPP4) inhibitor used for treating type 2 diabetes mellitus.
In vivo
Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s.Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a Tmax of 3-4 h and a half-life of 10-13 h.
AliasPHX-1149 free base
Chemical Properties
Molecular Weight241.1
FormulaC10H20BN3O3
Cas No.852329-66-9
Relative Density.1.24 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Dutogliptin | purchase Dutogliptin | Dutogliptin cost | order Dutogliptin | Dutogliptin chemical structure | Dutogliptin in vivo | Dutogliptin formula | Dutogliptin molecular weight