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DXR Inhibitor 11a sodium

Name: DXR Inhibitor 11a sodium
Brand: TargetMol
SKU: T83885
Rating: 4.5 (1 reviews)

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Catalog No. T83885

Alias 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a

DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum's growth in isolated human erythrocytes, with an IC50 of 0.37 µM.

DXR Inhibitor 11a sodium

😃Good

Catalog No. T83885Alias 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a

Pack Size	Price	Availability	Quantity
1 mg	$319	Backorder
5 mg	$1,110	Backorder

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum's growth in isolated human erythrocytes, with an IC50 of 0.37 µM.
Alias	1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a

Chemical Properties

Molecular Weight	279.20
Formula	C₁₀H₁₁NO₅P.Na

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Methanol: 10 mg/mL (35.82 mM), Sonication is recommended.

Ethanol: 10 mg/mL (35.82 mM), Sonication is recommended.

Solution Preparation Table

Methanol/Ethanol

	1mg	5mg	10mg	50mg
1 mM	3.5817 mL	17.9083 mL	35.8166 mL	179.0831 mL
5 mM	0.7163 mL	3.5817 mL	7.1633 mL	35.8166 mL
10 mM	0.3582 mL	1.7908 mL	3.5817 mL	17.9083 mL
20 mM	0.1791 mL	0.8954 mL	1.7908 mL	8.9542 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc