Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $135 | 35 days | |
5 mg | $578 | 35 days | |
10 mg | $987 | 35 days | |
25 mg | $2,230 | 35 days |
Description | Mild oxidation can convert the sulfhydryl group of cysteine residues on proteins to cysteine-sulfenic acid derivatives (Cys-SOH). Protein sulfenylation, then, is a post-translational modification that is relevant to redox signaling. DYn-2 is a chemoselective probe for detecting sulfenylated proteins in intact cells. DYn-2 consists of 1,3-cyclohexanedione coupled to an alkyne moiety by a 3-carbon spacer. The cyclohexanedione group selectively reacts with protein sulfenic acid modifications. The alkyne group of DYn-2 can then be detected using azide-bearing tags by standard click chemistry. This approach offers superior sensitivity relative to using azide-modified probes with alkynyl detection tags. |
Molecular Weight | 178.2277 |
Formula | C11H14O2 |
Cas No. | 1354630-46-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMF: 30 mg/mL Ethanol: 20 mg/mL DMSO: 20 mg/mL |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.