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E-​6123

Catalog No. T15188Cas No. 131614-02-3

E-6123 is an antagonist of platelet-activating factor (PAF) receptor.

E-​6123

E-​6123

Catalog No. T15188Cas No. 131614-02-3
E-6123 is an antagonist of platelet-activating factor (PAF) receptor.
Pack SizePriceAvailabilityQuantity
25 mg$1,9708-10 weeks
50 mg$2,5808-10 weeks
100 mg$3,4008-10 weeks
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Product Introduction

Bioactivity
Description
E-6123 is an antagonist of platelet-activating factor (PAF) receptor.
In vitro
E-6123 mitigates the Thapsigargin-induced elevation of interleukin-6 mRNA and protein levels to some extent. Specifically, at concentrations of 1 and 10 μM, E-6123 curtails the rise in interleukin-6 mRNA levels and protein production induced by Thapsigargin (46.1 nM) at 4 and 8 hours, respectively. The investigation into E-6123, a PAF receptor antagonist, aims to elucidate its influence on Thapsigargin’s effect on interleukin-6 mRNA and protein levels, particularly regarding the role of simultaneously generated cell-associated PAF.
Chemical Properties
Molecular Weight451.97
FormulaC23H22ClN5OS
Cas No.131614-02-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

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