Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Ecamsule disodium

Ecamsule disodium
Ecamsule disodium is a versatile UVA filter compound commonly employed in the formulation of sunscreen products. Its primary role is to mitigate the potential harm posed by solar radiation through the prevention of various biological repercussions induced by UV exposure. These include the inhibition of pyrimidine dimer formation, the reduction of p53 protein accumulation, and the downregulation of collagenase 2 expression.
Catalog No. T41037Cas No. 90458-75-6
Contact us for more batch information
Resource Download

Ecamsule disodium

Catalog No. T41037Cas No. 90458-75-6
Ecamsule disodium is a versatile UVA filter compound commonly employed in the formulation of sunscreen products. Its primary role is to mitigate the potential harm posed by solar radiation through the prevention of various biological repercussions induced by UV exposure. These include the inhibition of pyrimidine dimer formation, the reduction of p53 protein accumulation, and the downregulation of collagenase 2 expression.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
50 mgInquiry7-10 days
100 mgInquiry7-10 days
Bulk & Custom
Add to Cart
Questions
View More

Product Introduction

Bioactivity
Description
Ecamsule disodium is a versatile UVA filter compound commonly employed in the formulation of sunscreen products. Its primary role is to mitigate the potential harm posed by solar radiation through the prevention of various biological repercussions induced by UV exposure. These include the inhibition of pyrimidine dimer formation, the reduction of p53 protein accumulation, and the downregulation of collagenase 2 expression.
In vitro
Ecamsule, a broad-spectrum UVA-absorber with optimal absorbance at 344 nm, demonstrates increased sensitivity in wild-type Fibs E6/E7 cells at concentrations ranging from 200-1600 μM. It effectively mitigates UV and AAPH-induced ROS formation in fibroblasts, also reducing basal ROS levels in a dose-dependent manner. Maximum ROS reduction observed is 25.7% at 1600 μM under UV exposure. The same concentration decreases oxidative stress induced by AAPH by 10.8% and lowers basal ROS by 16.9%. Significantly, Ecamsule enhances cell viability at 1600 μM in AAPH-challenged cells.
Chemical Properties
Molecular Weight585.68
FormulaC28H34NaO8S2
Cas No.90458-75-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Ecamsule disodium | purchase Ecamsule disodium | Ecamsule disodium cost | order Ecamsule disodium | Ecamsule disodium chemical structure | Ecamsule disodium in vitro | Ecamsule disodium formula | Ecamsule disodium molecular weight