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EGFR-IN-36

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Catalog No. T63265Cas No. 2711105-54-1

EGFR-IN-36 is a potent inhibitor of EGFR, acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), and HER2 (A775_G776insYVMA) (IC50: 2.35 nM). EGFR-IN-36 exhibits potential for studying wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.

EGFR-IN-36

EGFR-IN-36

😃Good
Catalog No. T63265Cas No. 2711105-54-1
EGFR-IN-36 is a potent inhibitor of EGFR, acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), and HER2 (A775_G776insYVMA) (IC50: 2.35 nM). EGFR-IN-36 exhibits potential for studying wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.
Pack SizePriceAvailabilityQuantity
25 mg$1,520 8-10 weeks
50 mg$1,980 8-10 weeks
100 mg$2,500 8-10 weeks
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Product Introduction

Bioactivity
Description
EGFR-IN-36 is a potent inhibitor of EGFR, acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), and HER2 (A775_G776insYVMA) (IC50: 2.35 nM). EGFR-IN-36 exhibits potential for studying wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.
Chemical Properties
Molecular Weight488.97
FormulaC26H25ClN6O2
Cas No.2711105-54-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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