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EIF2α activator 2

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Catalog No. T62637Cas No. 1501618-04-7

EIF2α activator 2 (Compound 1) is a phosphorylated activator of eukaryotic initiation factor 2α (eIF2α), exhibiting anti-proliferative effects in K562 cells (IC50: 4.79 μM) and PBMC cells (IC50: 10.52 μM).

EIF2α activator 2

EIF2α activator 2

😃Good
Catalog No. T62637Cas No. 1501618-04-7
EIF2α activator 2 (Compound 1) is a phosphorylated activator of eukaryotic initiation factor 2α (eIF2α), exhibiting anti-proliferative effects in K562 cells (IC50: 4.79 μM) and PBMC cells (IC50: 10.52 μM).
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2 mg$925 days
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Product Introduction

Bioactivity
Description
EIF2α activator 2 (Compound 1) is a phosphorylated activator of eukaryotic initiation factor 2α (eIF2α), exhibiting anti-proliferative effects in K562 cells (IC50: 4.79 μM) and PBMC cells (IC50: 10.52 μM).
Chemical Properties
Molecular Weight446.39
FormulaC21H20F6N2O2
Cas No.1501618-04-7
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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