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Elisidepsin

Elisidepsin
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Elisidepsin

Catalog No. T82479Cas No. 681272-30-0
Elisidepsin (PM02734), a cyclic depsipeptide, exhibits antineoplastic activity by inhibiting cancer cell proliferation and is under research for the treatment of various cancers, including non-small cell lung cancer (NSCLC) [1] [2] [3] [4].
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Product Introduction

Bioactivity
Description
Elisidepsin (PM02734), a cyclic depsipeptide, exhibits antineoplastic activity by inhibiting cancer cell proliferation and is under research for the treatment of various cancers, including non-small cell lung cancer (NSCLC) [1] [2] [3] [4].
In vitro
Elisidepsin, administered over 72 hours, suppresses the proliferation of diverse cancer cell types, demonstrating half-maximal inhibitory concentration (IC50) values starting from 0.
In vivo
Elisidepsin administered intravenously at a dose of 100 µg/kg demonstrates efficacy in inhibiting lung cancer xenografts [3].
AliasPM02734
Chemical Properties
Molecular Weight1477.87
FormulaC75H124N14O16
Cas No.681272-30-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc