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endo-BCN-PEG2-acid, a PEG-based linker for PROTACs, connects two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $74 | 2-4 weeks | |
5 mg | $175 | 2-4 weeks | |
10 mg | $257 | 2-4 weeks | |
25 mg | $432 | 2-4 weeks | |
50 mg | $639 | 2-4 weeks | |
100 mg | $909 | 2-4 weeks |
Description | endo-BCN-PEG2-acid, a PEG-based linker for PROTACs, connects two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands connected by a linker: one binding to an E3 ubiquitin ligase and the other to the target protein. Utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins. |
Molecular Weight | 353.41 |
Formula | C18H27NO6 |
Cas No. | 1993134-72-7 |
Relative Density. | 1.21 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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