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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | endo-BCN-PEG2-C2-NHS ester is a PEG-based linker for PROTACs that connects two critical ligands, essential for the formation of PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase and the other targets the desired protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins [PROTACs]. |
Molecular Weight | 450.48 |
Formula | C22H30N2O8 |
Cas No. | 2243565-12-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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