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endo-BCN-PEG8-acid, a PEG-based linker, is pivotal for PROTAC molecules, connecting two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $84 | 4-6 weeks | |
5 mg | $196 | 4-6 weeks | |
10 mg | $295 | 4-6 weeks | |
25 mg | $498 | 4-6 weeks | |
50 mg | $863 | 4-6 weeks | |
100 mg | $1,170 | 4-6 weeks |
Description | endo-BCN-PEG8-acid, a PEG-based linker, is pivotal for PROTAC molecules, connecting two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. Utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1]. |
Molecular Weight | 617.73 |
Formula | C30H51NO12 |
Cas No. | 2126805-02-3 |
Relative Density. | 1.19 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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