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Enloplatin

Name: Enloplatin
Brand: TargetMol
SKU: T68065
Price: 76 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T68065Cas No. 111523-41-2

Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.

Enloplatin

🥰Excellent

Purity: 99.73%

Catalog No. T68065Cas No. 111523-41-2

Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.

Pack Size	Price	Availability
1 mg	$76	In Stock
5 mg	$177	In Stock
10 mg	$260	In Stock
25 mg	$506	In Stock
50 mg	$690	In Stock
100 mg	$982	In Stock
500 mg	$1,970	In Stock

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Purity:99.73%

Resource Download

COA HNMR HPLC LCMS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.
Targets&IC50	Tera (cells):7.2 µM
In vivo	Enloplatin (i.v. infusion; over 1.5 h; every 21 days), one patient had a partial response (6%; 95% CI 0-26%) lasting 2.8 months. The median survival was 9.4 months (95%; CI 5.1-19.7%). Neutropenia was the dose-limiting toxicity. Nephrotoxicity was manageable. Enloplatin is the major form of the free drug in plasma. However, 13.5 h after initiation of treatment, 85% of the drug in plasma is protein bound. Elimination of the drug is mainly renal.[1]

Chemical Properties

Molecular Weight	481.4
Formula	C₁₃H₂₂N₂O₅Pt
Cas No.	111523-41-2
Smiles	O=C1C2(C(=O)[O-][Pt+2]3([O-]1)[NH2]CC4(C[NH2]3)CCOCC4)CCC2

Storage & Solubility Information

Storage

keep away from direct sunlight | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (114.25 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0773 mL	10.3864 mL	20.7727 mL	103.8637 mL
5 mM	0.4155 mL	2.0773 mL	4.1545 mL	20.7727 mL
10 mM	0.2077 mL	1.0386 mL	2.0773 mL	10.3864 mL
20 mM	0.1039 mL	0.5193 mL	1.0386 mL	5.1932 mL
50 mM	0.0415 mL	0.2077 mL	0.4155 mL	2.0773 mL
100 mM	0.0208 mL	0.1039 mL	0.2077 mL	1.0386 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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