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ERD03 is a selective compound targeting EXOSC3, disrupting EXOSC3-RNA interactions in a concentration-dependent manner, useful in brain neurodegenerative disease research.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,500 | 1-2 weeks |
Description | ERD03 is a selective compound targeting EXOSC3, disrupting EXOSC3-RNA interactions in a concentration-dependent manner, useful in brain neurodegenerative disease research. |
In vitro | Methods: ERD03 (50 μM) was incubated with EXOSC3 and several concentrations of long G-rich RNA. The effect of ERD03 on the RNA/EXOSC3 interaction was tested using MST to measure the inhibitory effect of ERD03. Results: ERD03 reduced the binding of EXOSC3 to long G-rich RNA at several RNA concentrations; at 3.1 μM RNA, ERD03 inhibited the binding by 54%, in a concentration-dependent manner and similar inhibition was observed with long G-rich RNA. [1] |
Alias | ERD 03 |
Molecular Weight | 339.43 |
Formula | C21H25NO3 |
Cas No. | 1377897-01-2 |
Smiles | O=C(C1=CC=CC(=C1)CCC(O)(C)C)N2CC=3C=CC=CC3C(O)C2 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (235.69 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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